My contribution widens the horizon to the political importance of “other” forms of knowledge aiming to know the future in the age of the Counter-Reformation.In the definition and classification of them, prophecy plays an important role.At the end of the 16th century, in fact, prophecy becomes a comparison element in the classification of the f
Huntington disease (HD) is a fatal, neurodegenerative genetic disorder with aggregation of mutant Huntingtin protein (mutHTT) in the brain as a key pathological mechanism.There are currently no disease modifying therapies for HD; however, HTT-lowering therapies hold promise.Recombinant adeno-associated virus serotype 5 expressing a microRNA that ta
Human NAD(P)H-quinone oxidoreductase1 (HNQO1) is a two-electron reductase antioxidant enzyme whose expression is driven by the NRF2 transcription factor highly active in the prooxidant milieu found in human malignancies.The resulting abundance of NQO1 expression (up to 200-fold) in cancers and a barely detectable expression in body tissues makes it